Central Retinal Vein Occlusion

You probably know that high blood pressure and other vascular diseases pose risks to overall health, but you may not know that they can affect eyesight by damaging the veins in the eye.

Central retinal vein occlusion (CRVO) blocks the main vein in the retina, the light-sensitive nerve layer at the back of the eye. The blockage causes the walls of the vein to leak blood and excess fluid into the retina. When this fluid collects in the macula (the area of the retina responsible for central vision), vision becomes blurry.

“Floaters” in your vision are another symptom of CRVO. When retinal blood vessels are not working properly, the retina grows new fragile vessels that can bleed into the vitreous, the fluid that fills the center of the eye. Blood in the vitreous clumps and is seen as tiny dark spots, or floaters, in the field of vision.

In severe cases of CRVO, the blocked vein causes painful pressure in the eye. Retinal vein occlusions commonly occur with glaucoma, diabetes, age-related vascular disease, high blood pressure, and blood disorders.

The first step of treatment is finding what is causing the vein blockage. There is no cure for CRVO, though recent innovations have led to a significant improvement in the visual outcomes. Anti-vascular endothelial growth factor (anti-VEGF) injections have become the treatment of choice in managing patients with swelling in their retina from CRVO. These injections have shown a significant improvement in vision in many cases. Laser surgery may be effective in preventing further bleeding into the vitreous or for treating glaucoma, but it cannot remove a hemorrhage or cure glaucoma once it is present. New experimental treatments are now under investigation as well.